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Current Concepts in the Treatment of Diabetic Macular Edema

Ursula Schmidt-Erfurth, MD


The retina specialty is morphing at extraordinary rates and is mainly being driven by the large-scale research efforts leading to new therapeutic strategies and several candidates in the clinical development pipeline. Diabetic macular edema (DME) is one of several therapeutic areas in which new data are emerging. Results from several clinical studies assessing the safety and efficacy of different steroids utilizing different delivery methods for the management of DME have been recently announced and others will be reported in the near future. There are also new results from trials utilizing laser therapy, vascular endothelial growth factor inhibitors, and other approaches. Such influx of new data presents a challenge for the retina community: the ability of clinicians to keep up with the emerging data. In order for clinicians to effectively treat patients with DME, the educational gap between the most recent clinical research and results and disseminating those results to clinicians must be filled. This CME activity is designed to help retina specialists aggregate, interpret, and apply the new data to their clinical practice.


To provide retina specialists with up-to-date information on the management of DME.


This activity is designed for retina specialists. No prerequisites required.


After completing this activity, the participant will demonstrate the ability to:

  • SUMMARIZE the results of the latest clinical trials for the management of DME.
  • APPLY the latest clinical evidence on the management of macular edema in clinical case scenarios.

The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.


The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.


The Johns Hopkins University School of Medicine designates this educational activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

After reviewing this online activity, participants may receive credit by completing the CME test, evaluation, and responding to the post-test questions correctly.

The estimated time to complete this activity: 30 minutes.

Release date: June 30, 2010. Expiration date: June 30, 2012.


As a provider accredited by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine to require the disclosure of the existence of any significant financial interest or any other relationship a faculty member or a provider has with the manufacturer(s) of any commercial product(s) discussed in an educational presentation. The Chairperson and Participating Faculty reported the following:

Quan Dong Nguyen, MD, MSc (Chair)
Associate Professor of Ophthalmology
Diseases of the Retina and Vitreous, and Uveitis
Wilmer Eye Institute
Johns Hopkins University School of Medicine
Baltimore, Maryland

Ursula Schmidt-Erfurth, MD
Vorstand der Univ.-Klinik für Augenheilkunde und Optometrie
Professor and Chair
Medical University of Vienna
Department of Ophthalmology
Vienna, Austria

Participating Faculty Disclosures
Dr Schmidt-Erfurth reports serving as the principal investigator in VIEW2, GATE, MIZAR, GALILEO, MONTBLANC, RESTORE, RAD, MIVI5, WALTZ, VEFT-OD-0706 Microperimetry, DAVINCI for Alcon, Bayer, Novartis and Regeneron; serving as a consultant for and receiving honoraria from Alcon, Inc, Bayer, Novartis, and Pfizer Inc; and receiving patent royalties from QLT Inc.

Planner Disclosures
Dr Nguyen reports serving as a principal investigator on grants from Genentech, Inc, Heidelberg, Lux Biosciences, Inc, MacuSight, Inc, Novartis, and Regeneron Pharmaceuticals, Inc; and serving as a consultant for Bausch & Lomb, Incorporated and Santen Pharmaceutical Co, Ltd.

Dr Do reports serving as a principal investigator for grants/research support for Genentech Inc, Heidelberg, and Regeneron Pharmaceuticals, Inc; and serving as a consultant for Bausch & Lomb Incorporated.

No other planners have indicated that they have any financial interests or relationships with a commercial entity.

Grants to investigators at The Johns Hopkins University are negotiated and administered by the institution that receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).


No faculty member has indicated that their presentation will include information on off-label products.


The opinions and recommendations expressed by faculty and other experts whose input is included in this activity are their own. This activity is produced for educational purposes only. Use of Johns Hopkins University School of Medicine name implies review of educational format, design, and approach. Please review the complete prescribing information of specific drugs or combinations of drugs, including indications, contraindications, warnings, and adverse effects before administering pharmacologic therapy to patients.


The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protect the privacy of its members and customers. Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals, and the public. Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based activity. Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine’s CME activity. CME collects only the information necessary to provide you with the services that you request.



Please complete the pre-test, listen to the following presentations, and complete the post-test and evaluation to receive CME credit for this activity.

Supported by an educational grant from Allergan, Inc.

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