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Presented by the Johns Hopkins University School of Medicine.

This educational activity is supported by an educational grant from Allergan, Inc.

GOAL

To provide eye care professionals including ophthalmologists, comprehensive ophthalmologists, cornea specialists, cataract surgeons, glaucoma specialists, retina specialists, and optometrists with up-to-date information on the treatment and management of dry eye disease.

INTENDED AUDIENCE

This activity is designed for eye care professionals including ophthalmologists, comprehensive ophthalmologists, cornea specialists, cataract surgeons, glaucoma specialists, retina specialists, and optometrists. No prerequisites required.

LEARNING OBJECTIVE

After completing this activity, the participant will demonstrate the ability to:

  • Assess the importance of early diagnosis and treatment in the management of ocular surface diseases based on factors associated with a high risk for their development.
  • Recognize the impact of ocular surface diseases on the quality of life and the productivity of patients.
  • Determine the impact of different treatment strategies on disease progression in dry eye patients with ocular surface diseases.
  • Evaluate the recent guidelines and clinical evidence with regard to the diagnosis, classification, and management of ocular surface diseases.

The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

ACCREDITATION STATEMENT

The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENT

The Johns Hopkins University School of Medicine designates this enduring material for a maximum of 2 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The estimated time to complete this educational activity: 2 hours.

Release date: October 31, 2011. Expiration date: October 31, 2013.

HOW TO CLAIM CREDIT

Please complete a brief pre-assessment before continuing with the monograph. After reading this monograph, participants may receive credit by completing the CME test and evaluation online, and receiving a score of 70% or higher.

Faculty
Full Disclosure Policy Affecting CME Activities:
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME. Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity. Faculty are required to disclose only those relationships that are relevant to their specific presentation. The following relationships have been reported for this activity:

COURSE DIRECTOR AND PLANNER
Esen K. Akpek, MD

Associate Professor of Ophthalmology and Rheumatology
Director, Ocular Surface Diseases and Dry Eye Clinic
Wilmer Eye Institute
Johns Hopkins University School of Medicine

PARTICIPATING FACULTY
William J. Dupps, Jr, MD, PhD

Staff, Ophthalmology, Biomedical Engineering and Transplant
Cleveland Clinic
Adjunct Associate Professor, Biomedical Engineering
Case Western Reserve University

John J. Huang, MD
Associate Professor
Yale University, Department of Ophthalmology
Residency Program Director
Director of Ocular Immunology and Uveitis Service
Co-Director of Vitreo-Retinal Service
Director of Clinical Trials and Translational
Research Associate Director of Yale Bahamas Program

Marguerite McDonald, MD, FACS
Clinical Professor of Ophthalmology
NYU Langone Medical Center
Adjunct Clinical Professor of Ophthalmology
Tulane University Health Sciences Center
Cornea/Refractive/Anterior Segment Specialist
Ophthalmic Consultants of Long Island

Peter J. McDonnell, MD
William Holland Wilmer Professor of Ophthalmology
Director, Wilmer Eye Institute
Johns Hopkins University School of Medicine

Christopher J. Rapuano, MD
Director, Cornea Service
Co-director, Refractive Surgery Department
Wills Eye Institute
Professor, Jefferson Medical College of
Thomas Jefferson University

Pradeep Ramulu, MD, MHS, PhD (Planner)
Assistant Professor of Ophthalmology
Wilmer Eye Institute
Johns Hopkins University School of Medicine

Debra Schaumberg, ScD, OD, MPH
Associate Epidemiologist and Director
Ophthalmic Epidemiology, Division of Preventive Medicine
Brigham and Women’s Hospital
Associate Professor of Medicine and Ophthalmology
Harvard Medical School

Debra Gordon, MS
Medical Writer

Participating Faculty Disclosures
Dr Akpek reports serving as the principal investigator for research supported by Allergan, Inc, Inspire Pharmaceuticals, Inc, and Pfizer Inc; and receiving material support from TearLab.

Dr Dupps reports serving as a paid member of an internal roundtable discussion for Inspire Pharmaceuticals, Inc.

Dr McDonald reports serving as a consultant for Allergan, Inc, AMO, FOCUS Laboratories, and Inspire Pharmaceuticals, Inc; and receiving travel support from TearLab.

Dr McDonnell reports serving as a consultant for Allergan, Inc; and serving as a mentor of SAB for Advanced Medical Optics and Alcon Laboratories.

Dr Rapuano reports receiving honoraria from Alcon Laboratories, Allergan, Inc, Bausch & Lomb, Eyegate Pharma, and Inspire Pharmaceuticals, Inc.

Dr Schaumberg reports receiving a research grant from Pfizer Inc; serving as a consultant for Alcon Laboratories, Allergan, Inc, Celtic Pharma, Eleven Biotherapeutics, Inspire Pharmaceuticals, Inc, Pfizer Inc, and SARcode; and serving as an SAB member for SARcode.

No other speakers have indicated that they have any financial interests or relationships with a commercial entity whose products or services are relevant to the content of their presentation(s).

Planner Disclosures
Dr Akpek reports serving as the principal investigator for research supported by Allergan, Inc, Inspire Pharmaceuticals, Inc, and Pfizer Inc; serving as a consultant for Allergan, Inc, BioLux, Inspire Pharmaceuticals, Inc, and Pfizer Inc; and receiving material support from TearLab.

No other planners have indicated that they have any financial interests or relationships with a commercial entity.

Grants to investigators at The Johns Hopkins University are negotiated and administered by the institution that receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).


Off-Label Product Discussion: The following faculty members have disclosed that their presentation will reference unlabeled/unapproved use of drugs or products:

Dr McDonald: azithromycin and cyclosporine
Dr Rapuano: azithromycin drops for blepharitis/meibomitis; topical steroids for ocular surface and eyelid inflammation

DISCLAIMER
The opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own. This enduring material is produced for educational purposes only. Use of Johns Hopkins University School of Medicine name implies review of educational format design and approach. Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.
INTERNET CME POLICY
The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protect the privacy of its members and customers. Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals, and the public. Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based activity. Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine’s CME activity. CME collects only the information necessary to provide you with the services that you request.
Confidentiality Disclaimer for CME Activity Participant
I certify that I am participating in a Johns Hopkins University School of Medicine CME activity for accredited training and/or educational purposes.

I understand that while I am attending in this capacity, I may be exposed to "protected health information," as that term is defined and used in Hopkins policies and in the federal HIPAA privacy regulations (the "Privacy Regulations"). Protected health information is information about a person's health or treatment that identifies the person. I also understand that while I am participating in this capacity I will be treated as a temporary member of Johns Hopkins for purposes of the Privacy Regulations only.

I pledge and agree to use and disclose any of this protected health information only for the training and/or educational purposes of my visit and to keep the information confidential.

I understand that I may direct to the Johns Hopkins Privacy Officer any questions I have about my obligations under this Confidentiality Pledge or under any of the Hopkins policies and procedures and applicable laws and regulations related to confidentiality. The contact information is: Johns Hopkins Privacy Officer, telephone: 410-735-6509, e-mail: HIPAA@jhmi.edu.

“The Office of Continuing Medical Education at the Johns Hopkins University School of Medicine, as provider of this activity, has relayed information with the CME attendees/participants and certifies that the visitor is attending for training, education and/or observation purposes only.”

For CME Questions, please contact the CME Office (410) 955-2959 or e-mail cmenet@jhmi.edu.


Johns Hopkins University School of Medicine
Office of Continuing Medical Education
Turner 20/720 Rutland Avenue
Baltimore, Maryland 21205-2195
Reviewed & Approved by: General Counsel, Johns Hopkins Medicine (Updated 4/09)
HARDWARE & SOFTWARE REQUIREMENTS
Pentium 800 processor or greater, Windows 98/NT/200/XP or Mac OS 9/X or later, Microsoft Internet Explorer, Safari, Firefox, Windows Media Player 9.0 or later Flash player, 128 MB of RAM Monitor settings: High color at 800 x 600 pixels, Sound card and speakers, Adobe Acrobat Reader.
ACTIVITY
Instructions
The following activity consists of 3 sections: an unaccredited pre-test, a monograph, and a CME post-test and evaluation. All 3 sections must be completed to receive CME credit.

Pre-Test

Introduction
Ocular Surface Disease and Dry Eye: Methods for Improving Clinical Recognition and Patient Satisfaction

Esen K. Akpek, MD, and Debra Gordon, MS

Proceedings
Epidemiology of Ocular Surface Diseases and Dry Eye

Christopher J. Rapuano, MD

Dry Eye Progression and Management: Why Are Dry Eye Patients Undertreated?
Peter J. McDonnell, MD

The Impact of Ocular Surface Diseases on Quality of Life
Debra Schaumberg, ScD, OD, MPH

Review Article
The Economics of Treating Dry Eye

Marguerite McDonald, MD, FACS

Post-Test
procced to pretest
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